Almagro won 7-6 (3), 7-6 (5), 6-7 (5), 6-3 Thursday, despite Isner's 28 aces on Court 18. That was the site of Isner's record-breaking, 11-hour, 5-minute victory over Nicolas Mahut in the first round at the All England Club in 2010, a match that ended 70-68 in the fifth set.
In a rematch of the longest match, Isner beat Mahut in the first round this year, too.
But against Almagro, Isner never earned a single break point all match. Almagro earned the only service break to go ahead 2-0 in the fourth set.
Almagro had 63 winners and only 14 unforced errors. He finished with 25 aces.
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John Isner
http://accesswdun.com/article/2011/6/239807