partlycloudy
Thursday August 27th, 2015 3:21PM

NYC official: Hoffman died from toxic mix of drugs

By The Associated Press
NEW YORK (AP) -- Philip Seymour Hoffman died from taking a combination of heroin, cocaine and other drugs, the New York City medical examiner ruled Friday, a toxic mix that addiction specialists say is not uncommon in the tens of thousands of overdose deaths in the U.S. each year.

Hoffman, 46, who was found Feb. 2 with a needle in his arm on the floor of his Manhattan apartment, also had taken amphetamines and benzodiazepines, which are drugs such as Xanax and Valium that are widely prescribed for anxiety, trouble sleeping and other problems, said a spokeswoman for the medical examiner. The death was ruled accidental.

The medical examiner didn't provide the names of the drugs or the amounts found in the actor's system, making it impossible to determine which drug was the major factor, said Dr. Charles McKay, a medical toxicologist for Hartford Hospital in Connecticut and a spokesman for the American College of Medical Toxicology.

"There's a difference between a stimulant death, which would be cocaine and the amphetamines, and a narcotic death, like heroin," he said.

The first two can cause heart rhythm problems, a stroke or heart attack, whereas heroin, especially with sedatives such as benzodiazepines, can depress breathing.

In any case, McKay said, the combination of drugs "suggests someone who has been using drugs repetitively."

Police had been investigating Hoffman's death as a suspected drug overdose. Tests found heroin in samples from at least 50 packets in his Manhattan apartment. Authorities also found unused syringes, a charred spoon and various prescription medications, including a drug used to treat heroin addiction, a blood-pressure medication and a muscle relaxant.

More than half of overdose deaths in the U.S. involve a mix of drugs, said Dr. Len Paulozzi, a medical epidemiologist with the Centers for Disease Control and Prevention. At least a fifth also involve alcohol, he said. There were more than 38,000 drug overdose deaths nationwide in 2010, according to the most recent CDC figures.

If multiple drugs are listed on a death certificate, often "it means the coroner or medical examiner thought all of these contributed to the death," said Paulozzi, who researches overdose death trends.

"The drug of that combination that is most associated with overdose death is heroin," said Cindy Kuhn, a pharmacology professor at Duke University. "People just stop breathing. It's especially dangerous in combination with other sedatives like the benzodiazepines."

Hoffman, who won an Oscar for "Capote" and starred in numerous other movies as well as New York stage productions, had been frank about struggling with substance abuse. He told CBS' "60 Minutes" in 2006 that had he used "anything I could get my hands on" before getting clean at age 22. But in interviews last year, he said he'd relapsed, had developed a heroin problem and had gone to rehab for a time.

Heroin addicts often mix heroin with a stimulant like cocaine - a practice known as speedballing - to break the effect of the opiate, said addiction specialist Dr. Louis Baxter, a former president of the American Society of Addiction Medicine.

"They're doing self-medication or self-regulation," said Baxter. "It's just a part and parcel of what happens with long-term abuse of substances: People will go from just their drug of choice to experimentation and `self-regulation' of other drugs."

A Hoffman family spokesperson didn't immediately return messages seeking comment. In his will, Hoffman bequeathed his estate to his longtime partner, Mimi O'Donnell, with a trust fund for their 11-year-old son. They also have two other children.

Investigators have been probing how Hoffman may have obtained the heroin. Tests found it was not cut with a dangerous additive such as fentanyl, a synthetic form of morphine used to intensify the high that has been linked to deaths in other states.

A musician, veteran jazz player Robert Vineberg, was charged amid the investigation into Hoffman's death with keeping a heroin stash in a lower Manhattan apartment. Vineberg, who has said he was a friend of the Tony Award-nominated Hoffman, hasn't been charged in Hoffman's death and has said he didn't sell him the heroin found in his apartment.
© Copyright 2015 AccessWDUN.com
All rights reserved. This material may not be published, broadcast, rewritten, or redistributed without permission.
Judge denies motions to move, delay Tsarnaev trial
Lawyers for Boston Marathon bombing suspect Dzhokhar Tsarnaev asked a federal appeals court Wednesday to overturn a judge's decision to not move his upcoming trial out of state.
10:02PM ( 7 months ago )
High court to adopt electronic filing of cases
The Supreme Court is belatedly developing an electronic filing system similar to those used in courts around the country, Chief Justice John Roberts said Wednesday in his annual end-of-year report.
7:57PM ( 7 months ago )
Storm brings snow, cold to West for New Year's
A blustery winter storm dumped snow and ice across the West on Wednesday, making driving treacherous in the mountains from California to the Rockies and forcing residents and party-goers in some usually sun-soaked cities to bundle up for a frosty New Year's.
5:19PM ( 7 months ago )
U.S. News
Grass fire impacts rush hour traffic on 985
Rush hour traffic on I-985 was slowed by a grass fire Wednesay afternoon with one lane closed while firefighters fought the blaze.
10:19PM ( 7 months ago )
Hall County conviction, sentencing to be reviewed by SCOGA
The State Supreme Court has agreed to hear the appeal of a Hall County man when they reconvene in January.
2:37PM ( 7 months ago )
Local/State News
US stocks rise after Chinese market surges
U.S. stocks climbed Thursday morning as investors took advantage of this week's big sell-off to add to their holdings. The stock market is rebounding from a sharp sell-off earlier that was triggered b...
12:41PM ( 2 hours ago )
Settlement reached in lawsuit over decade-old Gulf oil leak
NEW ORLEANS (AP) — Environmental groups and a New Orleans company that failed to end a decade-old oil leak in the Gulf of Mexico have reached a settlement agreement in a lawsuit over the slow-motion s...
12:32PM ( 2 hours ago )
The Latest: Kentucky clerk again refuses to grant license
MOREHEAD, Ky. (AP) — The latest in the refusal of a Kentucky county clerk to issue marriage licenses to same-sex couples (all times local):___12 p.m.A Kentucky county clerk temporarily closed her offi...
12:07PM ( 3 hours ago )
Democratic Party lags in money before presidential year
WASHINGTON (AP) — The Democratic National Committee barely has more cash than it does IOUs, and it is being outraised month after month by its Republican competitor.Its $24 million debt from the 2012...
11:51AM ( 3 hours ago )
US stocks open higher after Chinese market surges
NEW YORK (AP) — U.S. stocks are opening higher after China's main stock index logged its biggest gain in eight weeks. A report also showed that the U.S. economy expanded at a much faster pace than pre...
9:42AM ( 5 hours ago )